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A Direct Role for FMRP in Activity-Dependent Dendritic mRNA Transport Links Filopodial-Spine Morphogenesis to Fragile X Syndrome
The function of local protein synthesis in synaptic plasticity and its dysregulation in fragile X syndrome (FSX) is well studied, however the contribution of regulated mRNA transport to this function remains unclear. We report a function for the fragile X mental retardation protein (FMRP) in the rap...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453222/ https://ncbi.nlm.nih.gov/pubmed/18539120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.04.003 |
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