A Direct Role for FMRP in Activity-Dependent Dendritic mRNA Transport Links Filopodial-Spine Morphogenesis to Fragile X Syndrome

The function of local protein synthesis in synaptic plasticity and its dysregulation in fragile X syndrome (FSX) is well studied, however the contribution of regulated mRNA transport to this function remains unclear. We report a function for the fragile X mental retardation protein (FMRP) in the rap...

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Hlavní autoři: Dictenberg, Jason B., Swanger, Sharon A., Antar, Laura N., Singer, Robert H., Bassell, Gary J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453222/
https://ncbi.nlm.nih.gov/pubmed/18539120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.04.003
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