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Delayed Stabilization of Dendritic Spines in Fragile X Mice
Fragile X syndrome (FXS) causes mental impairment and autism through transcriptional silencing of the Fmr1 gene, resulting in the loss of the RNA-binding protein fragile X mental retardation protein (FMRP). Cortical pyramidal neurons in affected individuals and Fmr1 knock-out (KO) mice have an incre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903441/ https://ncbi.nlm.nih.gov/pubmed/20534828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0577-10.2010 |
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