Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

Fragile X syndrome arises from blocked expression of the fragile X mental retardation protein (FMRP). Golgi-impregnated mature cerebral cortex from fragile X patients exhibits long, thin, tortuous postsynaptic spines resembling spines observed during normal early neocortical development. Here we des...

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Detalhes bibliográficos
Main Authors: Comery, Thomas A., Harris, Jennifer B., Willems, Patrick J., Oostra, Ben A., Irwin, Scott A., Weiler, Ivan Jeanne, Greenough, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24690/
https://ncbi.nlm.nih.gov/pubmed/9144249
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