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The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
Fragile X syndrome results from the transcriptional silencing of a gene, Fmr1, that codes for an mRNA-binding protein (fragile X mental retardation protein, FMRP) present in neuronal dendrites. FMRP can act as a translational suppressor, and its own translation in dendrites is regulated by group I m...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548595/ https://ncbi.nlm.nih.gov/pubmed/15684045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409803102 |
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