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The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
Fragile X syndrome results from the transcriptional silencing of a gene, Fmr1, that codes for an mRNA-binding protein (fragile X mental retardation protein, FMRP) present in neuronal dendrites. FMRP can act as a translational suppressor, and its own translation in dendrites is regulated by group I m...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684045/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409803102 |
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