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Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
Cholestasis is associated with accumulation of bile acids and lipids, and liver injury. The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors that coordinate protective hepatic responses to potentially toxic stimuli, including bile acids. We invest...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548592/ https://ncbi.nlm.nih.gov/pubmed/15684063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409794102 |
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