The Nuclear Receptors Constitutive Active/Androstane Receptor and Pregnane X Receptor Activate the Cyp2c55 Gene in Mouse Liver

Mouse CYP2C55 has been characterized as an enzyme that catalyzes synthesis of 19-hydroxyeicosatetraenoic acid (19-HETE), an arachidonic acid metabolite known to have important physiological functions such as regulation of renal vascular tone and ion transport. We have now found that CYP2C55 is induc...

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Autores principales: Konno, Yoshihiro, Kamino, Hiroki, Moore, Rick, Lih, Fred, Tomer, Kenneth B., Zeldin, Darryl C., Goldstein, Joyce A., Negishi, Masahiko
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908984/
https://ncbi.nlm.nih.gov/pubmed/20371638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.032334
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