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Phenytoin Induction of the Cyp2c37 Gene is Mediated by the Constitutive Androstane Receptor
The CYP2C subfamily of cytochrome P450 monoxygenases is responsible for the metabolism of approximately 20% of therapeutic drugs and many endogenous compounds in humans. These enzymes can be induced by prior treatment with drugs, resulting in changes in drug efficacy. Induction of human CYP2C enzyme...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1676033/ https://ncbi.nlm.nih.gov/pubmed/16936065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.106.012005 |
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