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The Role of Constitutive Androstane Receptor in Oxazaphosphorine-mediated Induction of Drug-metabolizing Enzymes in Human Hepatocytes
PURPOSE: The objective of this study was to investigate the roles of the constitutive androstane receptor (CAR) in cyclophosphamide (CPA)- and ifosfamide (IFO)-mediated induction of hepatic drug-metabolizing enzymes (DME). METHODS: Induction of DMEs was evaluated using real-time RT-PCR and Western b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703447/ https://ncbi.nlm.nih.gov/pubmed/21487929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0429-2 |
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