Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts

The crystal structure of Leishmania donovani tyrosyl-tRNA synthetase (LdTyrRS) in complex with a nanobody and the tyrosyl adenylate analog TyrSA was determined at 2.75 Å resolution. Nanobodies are the variable domains of camelid heavy chain-only antibodies. The nanobody makes numerous crystal contac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochimie
Egile Nagusiak: Barros-Álvarez, Ximena, Kerchner, Keshia M., Koh, Cho Yeow, Turley, Stewart, Pardon, Els, Steyaert, Jan, Ranade, Ranae M., Gillespie, J. Robert, Zhang, Zhongsheng, Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S., Hol, Wim G. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484532/
https://ncbi.nlm.nih.gov/pubmed/28427904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2017.04.006
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