Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts

The crystal structure of Leishmania donovani tyrosyl-tRNA synthetase (LdTyrRS) in complex with a nanobody and the tyrosyl adenylate analog TyrSA was determined at 2.75 Å resolution. Nanobodies are the variable domains of camelid heavy chain-only antibodies. The nanobody makes numerous crystal contac...

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Vydáno v:Biochimie
Hlavní autoři: Barros-Álvarez, Ximena, Kerchner, Keshia M., Koh, Cho Yeow, Turley, Stewart, Pardon, Els, Steyaert, Jan, Ranade, Ranae M., Gillespie, J. Robert, Zhang, Zhongsheng, Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S., Hol, Wim G. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484532/
https://ncbi.nlm.nih.gov/pubmed/28427904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2017.04.006
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