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Engineered allosteric ribozymes that respond to specific divalent metal ions

In vitro selection was used to isolate five classes of allosteric hammerhead ribozymes that are triggered by binding to certain divalent metal ion effectors. Each of these ribozyme classes are similarly activated by Mn(2+), Fe(2+), Co(2+), Ni(2+), Zn(2+) and Cd(2+), but their allosteric binding site...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Zivarts, Maris, Liu, Yong, Breaker, Ronald R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15681614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki182
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