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Engineered allosteric ribozymes that respond to specific divalent metal ions

In vitro selection was used to isolate five classes of allosteric hammerhead ribozymes that are triggered by binding to certain divalent metal ion effectors. Each of these ribozyme classes are similarly activated by Mn(2+), Fe(2+), Co(2+), Ni(2+), Zn(2+) and Cd(2+), but their allosteric binding site...

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Detaylı Bibliyografya
Asıl Yazarlar: Zivarts, Maris, Liu, Yong, Breaker, Ronald R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC548338/
https://ncbi.nlm.nih.gov/pubmed/15681614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki182
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