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Engineered Allosteric Ribozymes that Sense the Bacterial Second Messenger c-di-GMP
A series of allosteric ribozymes that respond to the bacterial second messenger cyclic di-guanosyl-5′-monophosphate (c-di-GMP) have been created by using in vitro selection. An RNA library was generated by using random-sequence bridges to join a hammerhead self-cleaving ribozyme to an aptamer from a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140410/ https://ncbi.nlm.nih.gov/pubmed/22519888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300415k |
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