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An Allosteric Self-splicing Ribozyme Triggered by a Bacterial Second Messenger

Group I self-splicing ribozymes commonly function as components of selfish mobile genetic elements. We identified an allosteric group I ribozyme, wherein self-splicing is regulated by a distinct riboswitch class that senses the bacterial second messenger c-di-GMP. The tandem RNA sensory system resid...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Lee, Elaine R., Baker, Jenny L., Weinberg, Zasha, Sudarsan, Narasimhan, Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538695/
https://ncbi.nlm.nih.gov/pubmed/20705859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190713
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