Cooperative binding of effectors by an allosteric ribozyme

An allosteric ribozyme that requires two different effectors to induce catalysis was created using modular rational design. This ribozyme construct comprises five conjoined RNA modules that operate in concert as an obligate FMN- and theophylline-dependent molecular switch. When both effectors are pr...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Jose, Antony M., Soukup, Garrett A., Breaker, Ronald R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11266567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.7.1631
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