Polyketide bio-derivatization using the promiscuous acyltransferase KirCII

During polyketide biosynthesis, acyltransferases (ATs) are the essential gatekeepers which provide the assembly lines with precursors and thus contribute greatly to structural diversity. Previously, we demonstrated that the discrete AT KirCII from the kirromycin antibiotic pathway accesses non-malon...

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Pubblicato in:ACS Synth Biol
Autori principali: Musiol-Kroll, Ewa M., Zubeil, Florian, Schafhauser, Thomas, Härtner, Thomas, Kulik, Andreas, McArthur, John, Koryakina, Irina, Wohlleben, Wolfgang, Grond, Stephanie, Williams, Gavin J., Lee, Sang Yup, Weber, Tilmann
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483334/
https://ncbi.nlm.nih.gov/pubmed/28206741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00341
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