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Polyketide bio-derivatization using the promiscuous acyltransferase KirCII

During polyketide biosynthesis, acyltransferases (ATs) are the essential gatekeepers which provide the assembly lines with precursors and thus contribute greatly to structural diversity. Previously, we demonstrated that the discrete AT KirCII from the kirromycin antibiotic pathway accesses non-malon...

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Bibliografiska uppgifter
I publikationen:ACS Synth Biol
Huvudupphovsmän: Musiol-Kroll, Ewa M., Zubeil, Florian, Schafhauser, Thomas, Härtner, Thomas, Kulik, Andreas, McArthur, John, Koryakina, Irina, Wohlleben, Wolfgang, Grond, Stephanie, Williams, Gavin J., Lee, Sang Yup, Weber, Tilmann
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483334/
https://ncbi.nlm.nih.gov/pubmed/28206741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00341
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