Polyketide bio-derivatization using the promiscuous acyltransferase KirCII

During polyketide biosynthesis, acyltransferases (ATs) are the essential gatekeepers which provide the assembly lines with precursors and thus contribute greatly to structural diversity. Previously, we demonstrated that the discrete AT KirCII from the kirromycin antibiotic pathway accesses non-malon...

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Udgivet i:ACS Synth Biol
Main Authors: Musiol-Kroll, Ewa M., Zubeil, Florian, Schafhauser, Thomas, Härtner, Thomas, Kulik, Andreas, McArthur, John, Koryakina, Irina, Wohlleben, Wolfgang, Grond, Stephanie, Williams, Gavin J., Lee, Sang Yup, Weber, Tilmann
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483334/
https://ncbi.nlm.nih.gov/pubmed/28206741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00341
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