Polyketide Proofreading by an Acyltransferase-like Enzyme

Trans-acyltransferase polyketide synthases (trans-AT PKSs) are an important group of bacterial enzymes producing bioactive polyketides. One difference from textbook PKSs is the presence of one or more free-standing AT-like enzymes. While one homolog loads the PKS with malonyl units, the function of...

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Autori principali: Jensen, Katja, Niederkrüger, Holger, Zimmermann, Katrin, Vagstad, Anna L., Moldenhauer, Jana, Brendel, Nicole, Frank, Sarah, Pöplau, Petra, Kohlhaas, Christoph, Townsend, Craig A., Oldiges, Marco, Hertweck, Christian, Piel, Jörn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400152/
https://ncbi.nlm.nih.gov/pubmed/22444588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.01.005
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