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Reprogramming acyl carrier protein interactions of an acyl-CoA promiscuous trans-acyltransferase

Protein interactions between acyl carrier proteins (ACP’s) and trans-acting acyltransferase domains (trans-AT’s) are critical for regioselective extender unit installation by many polyketide synthases. Yet, little is known regarding the specificity of these interactions, particularly for trans-AT’s...

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Detalhes bibliográficos
Main Authors: Ye, Zhixia, Musiol, Ewa M, Weber, Tilmann, Williams, Gavin J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035391/
https://ncbi.nlm.nih.gov/pubmed/24726832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.02.019
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