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Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use. Recent work suggested that epigenetic imprinting of Foxp3 and other Treg-specific signatur...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Garg, Garima, Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Toker, Aras, Ohkura, Naganari, Beckstette, Michael, Miyao, Takahisa, Geffers, Robert, Floess, Stefan, Gerdes, Norbert, Lutgens, Esther, Osterloh, Anke, Hori, Shohei, Sakaguchi, Shimon, Jaeckel, Elmar, Huehn, Jochen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482597/
https://ncbi.nlm.nih.gov/pubmed/28415767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16221
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