Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use. Recent work suggested that epigenetic imprinting of Foxp3 and other Treg-specific signatur...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Garg, Garima, Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Toker, Aras, Ohkura, Naganari, Beckstette, Michael, Miyao, Takahisa, Geffers, Robert, Floess, Stefan, Gerdes, Norbert, Lutgens, Esther, Osterloh, Anke, Hori, Shohei, Sakaguchi, Shimon, Jaeckel, Elmar, Huehn, Jochen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper: Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482597/
https://ncbi.nlm.nih.gov/pubmed/28415767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16221
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