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Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
Naturally arising regulatory CD4(+) T (Treg) cells, which specifically express the transcription factor FoxP3 in the nucleus and CD25 and CTLA-4 on the cell surface, are a T-cell subpopulation specialized for immune suppression, playing a key role in maintaining immunological self-tolerance and home...
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| Publicado no: | Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7264322/ https://ncbi.nlm.nih.gov/pubmed/32367041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0324-7 |
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