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Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes
Regulatory T (Treg) cells constitute a distinct T cell subset, which plays a key role in immune tolerance and homeostasis. The transcription factor Foxp3 controls a substantial part of Treg cell development and function. Yet its expression alone is insufficient for conferring developmental and funct...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650462/ https://ncbi.nlm.nih.gov/pubmed/23675373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00106 |
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