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Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
Most Foxp3(+) regulatory T (T(reg)) cells develop in the thymus as a functionally mature T cell subpopulation specialized for immune suppression. Their cell fate appears to be determined before Foxp3 expression; yet molecular events that prime Foxp3(−) T(reg) precursor cells are largely obscure. We...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582804/ https://ncbi.nlm.nih.gov/pubmed/27992401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3646 |
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