Wird geladen...
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
Foxp3-expressing regulatory T cells (Tregs) can be generated in vitro by antigenic stimulation of conventional T cells (Tconvs) in the presence of TGF-β and IL-2. However, unlike Foxp3(+) naturally occurring Tregs, such in vitro induced Tregs (iTregs) are functionally unstable mainly because of inco...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2020
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275710/ https://ncbi.nlm.nih.gov/pubmed/32414925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922600117 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|