Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use. Recent work suggested that epigenetic imprinting of Foxp3 and other Treg-specific signatur...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Garg, Garima, Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Toker, Aras, Ohkura, Naganari, Beckstette, Michael, Miyao, Takahisa, Geffers, Robert, Floess, Stefan, Gerdes, Norbert, Lutgens, Esther, Osterloh, Anke, Hori, Shohei, Sakaguchi, Shimon, Jaeckel, Elmar, Huehn, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482597/
https://ncbi.nlm.nih.gov/pubmed/28415767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16221
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