Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells

Regulatory T cells (Tregs) are potential immunotherapeutic candidates to induce transplantation tolerance. However, stability of Tregs still remains contentious and may potentially restrict their clinical use. Recent work suggested that epigenetic imprinting of Foxp3 and other Treg-specific signatur...

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Vydáno v:Oncotarget
Hlavní autoři: Garg, Garima, Nikolouli, Eirini, Hardtke-Wolenski, Matthias, Toker, Aras, Ohkura, Naganari, Beckstette, Michael, Miyao, Takahisa, Geffers, Robert, Floess, Stefan, Gerdes, Norbert, Lutgens, Esther, Osterloh, Anke, Hori, Shohei, Sakaguchi, Shimon, Jaeckel, Elmar, Huehn, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper: Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482597/
https://ncbi.nlm.nih.gov/pubmed/28415767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16221
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