The phospholipase iPLA(2)γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling

Cardiolipin (CL) is a dimeric phospholipid with critical roles in mitochondrial bioenergetics and signaling. Recently, inhibition of the release of oxidized fatty acyl chains from CL by the calcium-independent phospholipase A(2)γ (iPLA(2)γ)-selective inhibitor (R)-BEL suggested that iPLA(2)γ is resp...

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Vydáno v:J Biol Chem
Hlavní autoři: Liu, Gao-Yuan, Moon, Sung Ho, Jenkins, Christopher M., Li, Maoyin, Sims, Harold F., Guan, Shaoping, Gross, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481572/
https://ncbi.nlm.nih.gov/pubmed/28442572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783068
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