High-fat diet activates liver iPLA(2)γ generating eicosanoids that mediate metabolic stress

High-fat (HF) diet–induced obesity precipitates multiple metabolic disorders including insulin resistance, glucose intolerance, oxidative stress, and inflammation, resulting in the initiation of cell death programs. Previously, we demonstrated murine germline knockout of calcium-independent phosphol...

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Vydáno v:J Lipid Res
Hlavní autoři: Moon, Sung Ho, Dilthey, Beverly Gibson, Liu, Xinping, Guan, Shaoping, Sims, Harold F., Gross, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010217/
https://ncbi.nlm.nih.gov/pubmed/33636162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100052
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