Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A(2)γ (iPLA(2)γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size

Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids in myocardium. To specifically identify the rol...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Moon, Sung Ho, Mancuso, David J., Sims, Harold F., Liu, Xinping, Nguyen, Annie L., Yang, Kui, Guan, Shaoping, Dilthey, Beverly Gibson, Jenkins, Christopher M., Weinheimer, Carla J., Kovacs, Attila, Abendschein, Dana, Gross, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016701/
https://ncbi.nlm.nih.gov/pubmed/27453526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740597
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi