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Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice
Amyloid-β (Aβ) deposition is one of the hallmarks of the amyloid hypothesis in Alzheimer’s disease (AD). Mouse models using APP-transgene overexpression to generate amyloid plaques have shown to model only certain parts of the disease. The extent to which the data from mice can be transferred to man...
Shranjeno v:
| izdano v: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480119/ https://ncbi.nlm.nih.gov/pubmed/28637503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0448-2 |
| Oznake: |
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