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Expression of complement system components during aging and amyloid deposition in APP transgenic mice

BACKGROUND: A causal role of the complement system in Alzheimer's disease pathogenesis has been postulated based on the identification of different activated components up to the membrane attack complex at amyloid plaques in brain. However, histological studies of amyloid plaque bearing APP tra...

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Main Authors: Reichwald, Julia, Danner, Simone, Wiederhold, Karl-Heinz, Staufenbiel, Matthias
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784442/
https://ncbi.nlm.nih.gov/pubmed/19917141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-35
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