Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

Amyloid-β (Aβ) deposition is one of the hallmarks of the amyloid hypothesis in Alzheimer’s disease (AD). Mouse models using APP-transgene overexpression to generate amyloid plaques have shown to model only certain parts of the disease. The extent to which the data from mice can be transferred to man...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Steffen, Johannes, Krohn, Markus, Schwitlick, Christina, Brüning, Thomas, Paarmann, Kristin, Pietrzik, Claus U., Biverstål, Henrik, Jansone, Baiba, Langer, Oliver, Pahnke, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480119/
https://ncbi.nlm.nih.gov/pubmed/28637503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0448-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados