WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death

The WNT pathway mediates intercellular signaling that regulates cell fate in both normal development and cancer. It is widely appreciated that the WNT pathway is frequently dysregulated in human cancers through a variety of genetic and epigenetic mechanisms. Targets in the WNT pathway are being exte...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Fischer, Marcus M., Cancilla, Belinda, Yeung, V. Pete, Cattaruzza, Fiore, Chartier, Cecile, Murriel, Christopher L., Cain, Jennifer, Tam, Raymond, Cheng, Chieh-Yang, Evans, James W., O’Young, Gilbert, Song, Xiaomei, Lewicki, John, Kapoun, Ann M., Gurney, Austin, Yen, Wan-Ching, Hoey, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479655/
https://ncbi.nlm.nih.gov/pubmed/28691093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700090
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados