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Combinatorial biosynthesis of antitumor indolocarbazole compounds

Rebeccamycin and staurosporine are natural products with antitumor properties, which belong to the family of indolocarbazole alkaloids. An intense effort currently exists for the generation of indolocarbazole derivatives for the treatment of several diseases, including cancer and neurodegenerative d...

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Autores principales: Sánchez, César, Zhu, Lili, Braña, Alfredo F., Salas, Aaroa P., Rohr, Jürgen, Méndez, Carmen, Salas, José A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC544307/
https://ncbi.nlm.nih.gov/pubmed/15625109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407809102
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