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Combinatorial Biosynthesis of Antitumor Deoxysugar Pathways in Streptomyces griseus: Reconstitution of “Unnatural Natural Gene Clusters” for the Biosynthesis of Four 2,6-d-Dideoxyhexoses

Combinatorial biosynthesis was applied to Streptomyces deoxysugar biosynthesis genes in order to reconstitute “unnatural natural gene clusters” for the biosynthesis of four d-deoxysugars (d-olivose, d-oliose, d-digitoxose, and d-boivinose). Expression of these gene clusters in Streptomyces albus 16F...

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Detalhes bibliográficos
Main Authors: Pérez, María, Lombó, Felipe, Baig, Irfan, Braña, Alfredo F., Rohr, Jürgen, Salas, José A., Méndez, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610316/
https://ncbi.nlm.nih.gov/pubmed/17021216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01266-06
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