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Combinatorial Biosynthesis of Antitumor Deoxysugar Pathways in Streptomyces griseus: Reconstitution of “Unnatural Natural Gene Clusters” for the Biosynthesis of Four 2,6-d-Dideoxyhexoses
Combinatorial biosynthesis was applied to Streptomyces deoxysugar biosynthesis genes in order to reconstitute “unnatural natural gene clusters” for the biosynthesis of four d-deoxysugars (d-olivose, d-oliose, d-digitoxose, and d-boivinose). Expression of these gene clusters in Streptomyces albus 16F...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1610316/ https://ncbi.nlm.nih.gov/pubmed/17021216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01266-06 |
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