TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS

BACKGROUND: Histone deacetylases (HDACs) are crucial regulators of epigenetic and posttranslational modifications and therefore represent a promising therapeutic target in cancer cells that harbor distinct epigenomes from normal cells. To exploit the therapeutic potential of HDAC inhibitors (HDACi)...

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Foilsithe in:Neuro Oncol
Main Authors: Marquardt, Viktoria, Pauck, David, Hansen, Finn K., Picard, Daniel, Felsberg, Jörg, Reifenberger, Guido, Borkhardt, Arndt, Kurz, Thomas, Remke, Marc
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2017
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475212/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.238
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