Differential contribution of the three Aph1 genes to γ-secretase activity in vivo

γ-Secretase is the protease responsible for amyloid β peptide release and is needed for Notch, N-Cadherin, and possibly other signaling pathways. The protease complex consists of at least four subunits, i.e., Presenilin, Aph1, Pen2, and Nicastrin. Two different genes encode Aph1A and Aph1B in man. A...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Serneels, Lutgarde, Dejaegere, Tim, Craessaerts, Katleen, Horré, Katrien, Jorissen, Ellen, Tousseyn, Thomas, Hébert, Sébastien, Coolen, Marcel, Martens, Gerard, Zwijsen, An, Annaert, Wim, Hartmann, Dieter, De Strooper, Bart
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC547495/
https://ncbi.nlm.nih.gov/pubmed/15665098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408901102
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars