Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation

Hydroalkoxylation is a powerful and efficient method of forming C–O bonds and cyclic ethers in synthetic chemistry. In studying the biosynthesis of the fungal natural product herqueinone, we identified an enzyme that can perform an intramolecular enantio-selective hydroalkoxylation reaction. PhnH ca...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Gao, Shu-Shan, Garcia-Borràs, Marc, Barber, Joyann S., Hai, Yang, Duan, Abing, Garg, Neil K., Houk, K. N., Tang, Yi
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474393/
https://ncbi.nlm.nih.gov/pubmed/28240554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01089
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