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Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation

Hydroalkoxylation is a powerful and efficient method of forming C–O bonds and cyclic ethers in synthetic chemistry. In studying the biosynthesis of the fungal natural product herqueinone, we identified an enzyme that can perform an intramolecular enantio-selective hydroalkoxylation reaction. PhnH ca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Gao, Shu-Shan, Garcia-Borràs, Marc, Barber, Joyann S., Hai, Yang, Duan, Abing, Garg, Neil K., Houk, K. N., Tang, Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474393/
https://ncbi.nlm.nih.gov/pubmed/28240554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01089
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