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Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation

Hydroalkoxylation is a powerful and efficient method of forming C–O bonds and cyclic ethers in synthetic chemistry. In studying the biosynthesis of the fungal natural product herqueinone, we identified an enzyme that can perform an intramolecular enantio-selective hydroalkoxylation reaction. PhnH ca...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Gao, Shu-Shan, Garcia-Borràs, Marc, Barber, Joyann S., Hai, Yang, Duan, Abing, Garg, Neil K., Houk, K. N., Tang, Yi
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474393/
https://ncbi.nlm.nih.gov/pubmed/28240554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01089
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