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Copper-Catalyzed Enantioselective Hydroalkoxylation of Alkenols for the Synthesis of Cyclic Ethers

The copper-catalyzed enantioselective intramolecular hydroalkoxylation of unactivated alkenes for the synthesis of tetrahydrofurans, phthalans, isochromans, and morpholines from 4- and 5-alkenols is reported. The substrate scope is complementary to existing enantioselective alkene hydroalkoxylations...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Chen, Dake, Berhane, Ilyas A., Chemler, Sherry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541751/
https://ncbi.nlm.nih.gov/pubmed/32496794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01691
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