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Synthesis of Spirocyclic Ethers by Enantioselective Copper-Catalyzed Carboetherification of Alkenols
Spirocyclic ethers can be found in bioactive compounds. This copper-catalyzed enantioselective alkene carboetherification provides 5,5-, 5,6- and 6,6-spirocyclic products containing fully substituted chiral carbon centers with up to 99% enantiomeric excess. This reaction features the formation of tw...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Angew Chem Int Ed Engl |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375082/ https://ncbi.nlm.nih.gov/pubmed/30117646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201808554 |
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