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Chiral Indoline Synthesis Via Enantioselective Intramolecular Copper-Catalyzed Alkene Hydroamination

[Image: see text] An enantioselective copper-catalyzed hydroamination / cyclization of N-sulfonyl-2-allylanilines for the synthesis of chiral 2-methylindolines is reported. Chiral 2-methylindolines are important subunits in drugs and bioactive compounds. This method provides chiral N-sulfonyl-2-meth...

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Detalhes bibliográficos
Main Authors: Turnpenny, Benjamin W., Hyman, Kiante L., Chemler, Sherry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519432/
https://ncbi.nlm.nih.gov/pubmed/23243332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/om300744m
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