Caloric Restriction Extends Yeast Chronological Life Span by Optimizing the Snf1 (AMPK) Signaling Pathway

AMP-activated protein kinase (AMPK) and the homologous yeast SNF1 complex are key regulators of energy metabolism that counteract nutrient deficiency and ATP depletion by phosphorylating multiple enzymes and transcription factors that maintain energetic homeostasis. AMPK/SNF1 also promotes longevity...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Wierman, Margaret B., Maqani, Nazif, Strickler, Erika, Li, Mingguang, Smith, Jeffrey S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472825/
https://ncbi.nlm.nih.gov/pubmed/28373292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00562-16
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