A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae, CR is commonly defined by reduced glucose in the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Enriquez-Hesles, Elisa, Smith, Daniel L., Maqani, Nazif, Wierman, Margaret B., Sutcliffe, Matthew D., Fine, Ryan D., Kalita, Agata, Santos, Sean M., Muehlbauer, Michael J., Bain, James R., Janes, Kevin A., Hartman, John L., Hirschey, Matthew D., Smith, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949035/
https://ncbi.nlm.nih.gov/pubmed/33243834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015402
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