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Mitochondrial Respiratory Thresholds Regulate Yeast Chronological Lifespan and its Extension by Caloric Restriction

We have explored the role of mitochondrial function in aging by genetically and pharmacologically modifying yeast cellular respiration production during the exponential and/or stationary growth phases, and determining how this affects chronological lifespan (CLS). Our results demonstrate that respir...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ocampo, Alejandro, Liu, Jingjing, Schroeder, Elizabeth A., Shadel, Gerald S., Barrientos, Antoni
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397320/
https://ncbi.nlm.nih.gov/pubmed/22768839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.05.013
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