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Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan
Mitochondrial DNA (mtDNA) exists in multiple copies per cell and is essential for oxidative phosphorylation. Depleted or mutated mtDNA promotes numerous human diseases and may contribute to aging. Reduced TORC1 signaling in the budding yeast, Saccharomyces cerevisiae, extends chronological lifespan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943709/ https://ncbi.nlm.nih.gov/pubmed/24373996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2013.12.002 |
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